Either increases toxicity of the other by Other (see comment). pharmacodynamic antagonism. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug are: aliskiren, certain drugs that weaken the immune system/increase the risk of infection (such as everolimus, sirolimus), lithium, drugs that may increase the level of potassium in the blood (such as ARBs including losartan/valsartan, birth control pills containing drospirenone), sacubitril.Some products have ingredients that could raise your blood pressure or worsen your heart failure. Use Caution/Monitor. trimethoprim and lisinopril both increase serum potassium. Avoid or Use Alternate Drug. Comment: Coadministration of neprilysin inhibitors (eg, sacubitril) with ACE inhibitors may increase angioedema risk; do not administer ACE inhibitors within 36 hr of switching to or from sacubitril/valsartan. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Avoid or Use Alternate Drug. Tell your doctor if your condition does not get better or if it gets worse (for example, your blood pressure readings remain high or increase). Coadministration with drugs associated with nephrotoxicity may increase the risk for acute and/or chronic nephrotoxicity. Use Caution/Monitor. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Add 4 teaspoonfuls of water to the crushed KI powder in Enter your email address if you would like your recommendations emailed to you. Coadministration may result in a significant decrease in renal function. lornoxicam decreases effects of lisinopril by pharmacodynamic antagonism. Use Caution/Monitor. Use Caution/Monitor. oJBA &zEh#wcOp 4jv4{@,EC!5I*o+5+pEF=.\rf-|#]y/y6K^.]_G? Discontinue as soon as possible when pregnancy is detected; affects renin-angiotensin system, causing oligohydramnios, which may result in fetal injury and/or death, Hypersensitivity to lisinopril/other ACE inhibitors, History of ACE inhibitor-induced angioedema, hereditary or idiopathic angioedema, Coadministration of neprilysin inhibitors (eg, sacubitril), Coadministration with aliskiren in patients with diabetes mellitus or with renal impairment (ie, GFR <60 mL/min/1.73m, Anaphylactoid reactions reported in some patients dialyzed with high-flux membranes, Hematologic effects including agranulocytosis and neutropenia/agranulocytosis reported especially in patients with renal impairment and collagen vascular disease; monitor CBC periodically with differential, Excessive hypotension with concomitant diuretics, hypovolemia, hyponatremia may occur, Neprilysin inhibitors (eg, sacubitril) with ACE inhibitors may increase angioedema risk; do not administer ACE inhibitors within 36 hr of switching to or from sacubitril/valsartan, Risk of hyperkalemia, especially in patients with renal impairment or DM or in patients taking concomitant K+-elevating drugs, ACE inhibition also causes an increase in bradykinin levels, which putatively mediates angioedema; in comparison with other patients, a higher incidence of angioedema caused by ACE inhibitors has been observed in black patients, A dry hacking cough may occur within a few months of initiating drug therapy with ACE inhibitors; exclude other causes of cough before discontinuing therapy, Cholestatic jaundice associated with ACE inhibitors; discontinue if marked elevation of hepatic transaminases or jaundice occurs, Coadministration with mTOR inhibitors (eg, temsirolimus, everolimus) may increased risk for angioedema, Discontinue STAT if patient becomes pregnant, Use caution in patients with renal impairment; renal deterioration reported in patients with low renal blood flow, Use caution in patients with severe aortic stenosis, cardiovascular disease, collagen vascular disease, hypertrophic cardiomyopathy, Dual blockade of the renin-angiotensin-aldosterone system (ie, ARB plus an ACE inhibitor) in patients with established atherosclerotic disease or heart failure or with diabetes with end organ damage is associated with a higher frequency of hypotension, syncope, hyperkalemia, and changes in renal function (including acute renal failure), as compared with use of a single renin-angiotensin-aldosterone system agent; limit dual blockade to individually defined cases, with close monitoring of renal function, Neonates with history of in utero exposure: If oliguria or hypotension occurs, support of blood pressure and renal perfusion; exchange transfusions or dialysis may be required, Angioedema of the face, extremities, lips, tongue, glottis and/or larynx, including some fatal reactions, at any time during treatment; patients with involvement of the tongue, glottis or larynx are likely to experience airway obstruction, especially patients with history of airway surgery; promptly discontinue and provide appropriate therapy and monitoring until complete and sustained resolution of signs and symptoms of angioedema has occurred, Intestinal angioedema reported; patients presented with abdominal pain (with or without nausea or vomiting); in some cases there was no prior history of facial angioedema and C-1 esterase levels were normal; symptoms resolved after stopping the ACE inhibitor, Hypotension may occur sometimes complicated by oliguria, progressive azotemia, acute renal failure or death; patients at risk of excessive hypotension include heart failure with systolic blood pressure below 100 mmHg, ischemic heart disease, cerebrovascular disease, hyponatremia, high dose diuretic therapy, renal dialysis, or severe volume and/or salt depletion of any etiology; in such patients initiate therapy under medical supervision and follow such patients for the first two weeks of treatment and whenever dose of lisinopril and/or diuretic is increased; avoid use in patients who are hemodynamically unstable after acute MI; symptomatic hypotension also possible in patients with severe aortic stenosis or hypertrophic cardiomyopathy, Patients undergoing major surgery or during anesthesia with agents that produce hypotension, lisinopril may block angiotensin II formation secondary to compensatory renin release; if hypotension occurs and considered to be due to this mechanism, it can be corrected by volume expansion, Monitor renal function periodically; changes in renal function including acute renal failure can be caused by drugs that inhibit renin-angiotensin system; patients whose renal function may depend in part on activity of the renin-angiotensin system (eg, patients with renal artery stenosis, chronic kidney disease, severe congestive heart failure, post-myocardial infarction or volume depletion) may be at particular risk of developing acute renal failure; consider withholding or discontinuing therapy in patients who develop a clinically significant decrease in renal function, Therapy can cause fetal harm when administered to a pregnant woman; use of drugs that act on renin- angiotensin system during second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death, Most epidemiologic studies examining fetal abnormalities after exposure to antihypertensive use in first trimester have not distinguished drugs affecting renin- angiotensin system from other antihypertensive agents; when pregnancy is detected, discontinue therapy as soon as possible, No data are available regarding presence of lisinopril in human milk or effects on the breastfed infant or on milk production, The drug is present in rat milk; because many drugs are secreted in human milk, and because of thepotential for serious adverse reactions in breastfed infants from ACE inhibitors, discontinue breastfeeding or discontinue therapy. lisinopril increases effects of chlorpropamide by pharmacodynamic synergism. In 2012, Fleming Co. sold all its product rights and manufacturing facility to other companies and no longer exists. lisinopril and potassium citrate/citric acid both increase serum potassium. Use Caution/Monitor. Avoid or Use Alternate Drug. It is typically used to treat mild to moderate degrees of pain. Most people can take KI, but you should talk to your doctor before taking it. You could breathe in the radioiodine or eat food that has some radioiodine in it. Monitor Closely (1)trimethoprim and lisinopril both increase serum potassium. Coadministration may result in a significant decrease in renal function. ACE inhibitors may increase hypoglycemic effect. lisinopril, furosemide. Other (see comment). Comment: Coadministration results in additive risk of developing angioedema of face, mouth, and neck. )It is unknown if this medication passes into breast milk. Either increases effects of the other by pharmacodynamic synergism. Avoid or Use Alternate Drug. Minor/Significance Unknown. pharmacodynamic antagonism. Minor/Significance Unknown. Always ask your health care professional for complete information about this product and your specific health needs. [51] Because the volumes of KI and water are approximately additive, the resulting SSKI solution will contain about 1.00gram (1000mg) KI per milliliter (mL) of solution. Monitor Closely (1)lisinopril increases effects of insulin NPH by pharmacodynamic synergism. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Your doctor will check your kidney function while you are taking lisinopril. McCance; Huether. should not take KI. Use Caution/Monitor. Either increases toxicity of the other by Other (see comment). Use Caution/Monitor. Comment: Coadministration increases risk of angioedema. Get medical help right away if you have any symptoms of liver damage, such as: nausea/vomiting that doesn't stop, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine.A very serious allergic reaction to this drug is rare. Exaggerated first dose hypotensive response. lisinopril, sulindac. of an allergic reaction (difficulty breathing, speaking or swallowing; Coadministration may result in a significant decrease in renal function. Either increases toxicity of the other by Other (see comment). checked in babies less than 1 month of age that take KI. Since it is not a prescription drug, you can buy it over the Internet. Stability and Dose Uniformity Evaluations of Potassium Iodide Solid Dosage Tablets mixed in Drinks. [5][6] It is a supplement used by people with low dietary intake of iodine. [6] While use during pregnancy may harm the baby, its use is still recommended in radiation emergencies. radioactive iodine will enter your thyroid gland. Pharmacodynamics. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.Serious - Use Alternative (1)ketorolac, lisinopril. Properly discard this product when it is expired or no longer needed. NSAIDs decrease prostaglandin synthesis. pharmacodynamic antagonism. When amifostine is used at chemotherapeutic doses, withhold blood pressure lowering medications for 24 hr prior to amifostine; if blood pressure lowering medication cannot be withheld, do not administer amifostine. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. pharmacodynamic antagonism. Take potassium iodide (KI) only when public officials tell you. Minor (1)parecoxib decreases effects of lisinopril by pharmacodynamic antagonism. sodium sulfate/?magnesium sulfate/potassium chloride increases toxicity of lisinopril by Other (see comment). Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. promazine increases effects of lisinopril by unspecified interaction mechanism. Avoid or Use Alternate Drug. Use Caution/Monitor. Coadministration may result in a significant decrease in renal function. Use Caution/Monitor. piroxicam, lisinopril. To view formulary information first create a list of plans. Coadministration may result in a significant decrease in renal function. Coadministration may result in a significant decrease in renal function. Minor (1)cornsilk increases effects of lisinopril by pharmacodynamic synergism. Use Caution/Monitor. Either increases toxicity of the other by Other (see comment). "[39], Chernobyl also demonstrated that the need to protect the thyroid from radiation was greater than expected. Either increases toxicity of the other by Other (see comment). KI can come as a pill or a liquid. Minor/Significance Unknown. Minor/Significance Unknown. . Coadministration may result in a significant decrease in renal function. Mechanism: pharmacodynamic synergism. [38][18] However the US Nuclear Regulatory Commission (NRC) reported, "thousands of measurements of I-131 (radioactive iodine) activitysuggest that the observed levels were lower than would have been expected had this prophylactic measure not been taken. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.Serious - Use Alternative (1)flurbiprofen, lisinopril. Exaggerated first dose hypotensive response. Risk of hyperkalemia. Tablets of potassium iodide are supplied for emergency purposes related to blockade of radioiodine uptake, a common form of radiation poisoning due to environmental contamination by the short-lived fission product 131I. Consider decreasing dosage of antihypertensive agent. 25 mcg (1000 IU), 250 softgels Add To Cart Resveratrol Elite 30 vegetarian capsules. Minor/Significance Unknown. lisinopril increases levels of digoxin by unspecified interaction mechanism. stops. The New York State Health Department agrees. Potassium iodide is also not recommended for people with dermatitis herpetiformis and hypocomplementemic vasculitis conditions that are linked to a risk of iodine sensitivity. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. . To be effective in children, the drug/food or drug/drink mixture must have good stability and dose uniformity and have reasonable taste. They are named after their chemical structure, which contains three rings of atoms. Minor (1)creatine, lisinopril. Children who are adult size (greater than or equal to 150 pounds) should take the full adult dose, regardless of their age. Monitor Closely (1)methylphenidate transdermal decreases effects of lisinopril by anti-hypertensive channel blocking. Mechanism: pharmacodynamic synergism. Make sure all your doctors know which medicines you are using. NSAIDs decrease prostaglandin synthesis. Monitor Closely (1)lisinopril, insulin degludec. Minor/Significance Unknown. As formed under acidic conditions, hydriodic acid (HI) is a stronger reducing agent.[32][33][34]. lurasidone increases effects of lisinopril by Other (see comment). Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. It is found in pineapple juice and in the pineapple stem. Mechanism: pharmacodynamic synergism. U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Division of Pharmaceutical Analysis, 1114 Market St., Room 1002, St. Louis, MO 63101. Internet Explorer is no longer supported by many websites. aceclofenac decreases effects of lisinopril by pharmacodynamic antagonism. pharmacodynamic antagonism. lisinopril increases effects of insulin NPH by pharmacodynamic synergism. These compounds contain iodine, but not in the iodide form. However, for several fluorophores addition of KI in M-mM concentrations results in increase of fluorescence intensity, and iodide acts as fluorescence enhancer.[30]. In a few cases, babies had a reaction in their thyroids. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Potassium iodide saturates the thyroid gland with stable iodine. lisinopril, naproxen. Use Caution/Monitor. Minor/Significance Unknown. It is produced industrially by treating KOH with iodine.[31]. Either increases toxicity of the other by pharmacodynamic synergism. [7] Commercially it is made by mixing potassium hydroxide with iodine. ketorolac intranasal, lisinopril. Children 1 month to 3 years take one quarter (1/4) tablet. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.Serious - Use Alternative (1)salsalate, lisinopril. Use Caution/Monitor. Use Caution/Monitor. Minor/Significance Unknown. In the event of a radioiodine release the ingestion of prophylaxis potassium iodide, if available, or even iodate, would rightly take precedence over perchlorate administration, and would be the first line of defence in protecting the population from a radioiodine release. Coadministration may result in a significant decrease in renal function. lisinopril, piroxicam. Provides a high level of iodine (100 mg) in the form of potassium iodide, Potassium iodide saturates the thyroid gland with stable iodine, The shelf life of our Potassium Iodide Tablets is 24 months. Use Caution/Monitor. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen).A very serious reaction may occur if you are getting injections for bee/wasp sting allergy (desensitization) and are also taking lisinopril. Therapy with carbidopa, given with or without levodopa or carbidopa-levodopa combination products, is started, dosage adjustment of the antihypertensive drug may be required. Use Caution/Monitor. Use Caution/Monitor. octacosanol increases effects of lisinopril by pharmacodynamic synergism. It is not a good idea to take KI if you have certain medical conditions or problems. Use Caution/Monitor. naproxen, lisinopril. 130 mg. Other ingredients: microcrystalline cellulose, stearic acid, silica, vegetable stearate, pharmaceutical glaze. Use Caution/Monitor. Risk of hyperkalemia. Use Caution/Monitor. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. Use Caution/Monitor. swelling of various parts of the body such as the face, Avoid or Use Alternate Drug. shepherd's purse, lisinopril. tolfenamic acid decreases effects of lisinopril by pharmacodynamic antagonism. lisinopril, oxaprozin. pharmacodynamic antagonism. Monitor Closely (1)lisinopril increases effects of chlorpropamide by pharmacodynamic synergism. Coadministration may result in a significant decrease in renal function. Monitor Closely (1)lisinopril, aspirin. Potassium Iodide Radiation Tablets 130 mg (2 Pack) - (280 Tablets) EXP 05/2032 - Ki Pills Potassium Iodine Tablets for Radiation - Potassium Iodine Pills YODO Naciente, Anti Nuclear Fallout Pills 1.0 out of 5 stars Dosage other than specified. We have learned this from looking at children in Russia and other areas who were exposed to the radioiodine from the Chernobyl nuclear power plant accident. lisinopril, torsemide. Risk of hyperkalemia. NOT FOR DAILY USE. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Mechanism: pharmacodynamic synergism. Serious - Use Alternative (1)irbesartan, lisinopril. Serious - Use Alternative (1)candesartan, lisinopril. Coadministration may result in a significant decrease in renal function.