What makes a difference? Globans Pharma in no case is responsible for the content of the links in the website or links in the linked websites. Ans. In Australia, any unused medicine or waste material should be disposed of in accordance with local requirements. If you do not understand the instructions on the label ask your doctor or pharmacist for help. Contact the representative of the marketing authorization holder to find out more about this medicine: (adsbygoogle = window.adsbygoogle || []).push({}); What you need to know before you take Revolade, If you take more Revolade than you should, Contents of the pack and other information, What the medicine looks like and the contents of the pack, Inflammation and infection of the lungs and trachea, Voriconazole Teva Voriconazole uses, dose and side effects, Voriconazole Sandoz Voriconazole uses, dose and side effects, Voriconazole Fresenius Kabi Voriconazole uses, dose and side effects, Voriconazole Accord Voriconazole uses, dose and side effects, Voncento Humancoagulation factorVIII,humanvon Willebrand factor uses, dose and side effects, Voltaren Ophtha Diclofenac sodium uses, dose and side effects, Voltaren Diclofenac sodium uses, dose and side effects, Volibris Ambrisentan uses, dose and side effects, Vocabria Cabotegravir uses, dose and side effects, Vizimpro Dacomitinib uses, dose and side effects, VIZAMYL Flutemetamol uses, dose and side effects, Revolade is used to treat a bleeding disorder called, Revolade can also be used to treat lowplatelet counts. Revolade film-coated tablets contain eltrombopag olamine. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. If you experience symptoms such as sharp pain and swelling in the leg, difficulty breathing, chest pain, blurred vision, or difficulty speaking, contact your doctor immediately. Do not breastfeed while taking Revolade. This medicine is authorised for use in the European Union. Your doctor may want to test your liver function regularly with blood tests while you are taking this medication. Sore throat, runny nose, nasal congestion and sneezing, Infection in the nose, sinuses, throat and upper airways, common cold (upper respiratory tract). HOW LONG WILL IT TAKE FOR THE MEDICINE TO REACH AT HOME ? The following side effects have been reported by at least 1% of people taking this medication. There is no information regarding the safety and effectiveness of using this medication to treat chronic hepatitis C infection or severe aplastic anemia in children less than 18 years of age. Each film-coated tablet also contains magnesium stearate, mannitol, microcrystalline cellulose, povidone, sodium starch glycollate, hypromellose, macrogol 400, titanium dioxide, polysorbate 80 (12.5 mg tablet and 25 mg tablet only), iron oxide red CI77491 (50 mg tablet and 75 mg tablets only), iron oxide yellow CI77492 (50 mg tablet only) and iron oxide black CI77499 (75 mg tablet only). Our customer care person shall help you with making payments digitally without any hassle. My hair also started getting very thin so l had a word with my hairdresser who suggested using a medical shampoo and conditioner issued by a doctor which l did. You just need to fill in the inquiry form to get a callback from our representative. Eltrombopag is a small-molecule, orally bioavailable TPO-receptor agonist that interacts with the human TPO-transmembrane receptor's region. Chemical name: 3'-{(2Z)-2-[1-(3,4-dimethyl-phenyl)- 3-methyl-5-oxo-1,5-dihydro- 4H-pyrazol-4-ylidene]hydrazino}- 2'-hydroxy-3-biphenyl carboxylic acid-2-aminoethanol (1:2). Read our full disclaimer. Ongoing education for Aboriginal and Torres Strait Islander health workers and practitioners on quality use of medicines and medical tests, Practical information, tools and resources for health professionals and staff to help improve the quality of health care and safety for patients. . Do not be alarmed by these lists of possible side effects. change one of the medications to another, change how you are taking one or both of the medications, or. Thrombocytopenia associated with hepatitis C. For the treatment of thrombocytopenia associated with hepatitis C, two main studies involving a total of 1,441 adults were carried out. So I am fortunate that I have no major side effects from Eltrombopag. The increased speed of blood cell formation may cause certain blood diseases such as blood cancers to progress. Do not crush, break, or chew the tablet. Adult and adolescent patients 12 to 17 years of age: 150 mg once a day for 6 months. corticosteroids, immunoglobulins) (see sections4.2 and 5.1). If you want to ask a question or request information from EMA, please Send a question to the European Medicines Agency. It may be taken with food that contains very little or no calcium. All medicines have risks and benefits. Children who can swallow tablets may be prescribed this medication to treat ITP. Ans. For adultsandchildren(6-17 years) the usual starting dose for ITP isone 50 mg tabletof Revolade a day. Sorry to read of the side effects your are getting. Do not take Revolade with dairy products or milk drinks as thecalciumfound in dairy products affects the uptake of the medicine. After you have stopped taking REVOLADE, your bleeding symptoms may come back. In adult patients when other medicines to treat SAA have not worked well enough. Copyright 2022 IBM Watson Health. It is not known whether Revolade is excreted in human breast milk. The usual starting dose of REVOLADE for SAA patients when it is given with standard immunosuppressive therapy as the first treatment for severe SAA is: Your doctor will prescribe the appropriate immunosuppressive therapy in addition to REVOLADE. This dose may be increased every 2 weeks to a maximum of 150mg once daily. For the United Kingdom, as of 1 January 2021, European Union law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland / NI. Data from scientific literature supported these findings. If it has expired or is damaged, return it to your pharmacist for disposal. For the full list of restrictions and side effects of Revolade, see the package leaflet. Revolade is a medicine that is used for the treatment of: Revolade contains the active substance eltrombopag. How to store Revolade (Eltrombopag)? Does Revolade (Eltrombopag) cause any side effects? Take this medicine as per your doctors prescription. Q7. In the second study, the 135 patients taking Revolade were around 8 times more likely to reach the target platelet count of between 50,000 and 400,000 per microlitre during the 6 months of treatment than the 62 patients who were given placebo. If it is necessary to stop taking eltrombopag, your doctor should do regular blood tests to ensure that your platelet count does not fall too low. More intense colour of the skin (hyperpigmentation), Yellowing of the skin or whites of the eyes (due to jaundice or increased level of the pigment bilirubin in the blood), Polysorbate 80 (E433) (12.5 mg tablet and 25 mg tablet only), Iron oxide red CI77491 (E172) (50 mg tablet only). These side effects of Revolade are usually Episode 51: Quit smoking. There are limited data on the use of Revolade in patients 65 years of age and older. Ans. Do not give this medicine to anyone else, even if their condition seems to be the same as yours. All rights reserved. The main measure of effectiveness was the number of patients who responded to Revolade (whose platelet, red or white blood cell count remained above pre-set levels) after 12 or 16 weeks of treatment. Information given here is based on the salt content of the Revolade is indicated in adult patients with chronic hepatitisC virus (HCV) infection for the treatment of thrombocytopenia, where the degree of thrombocytopenia is the main factor preventing the initiation or limiting the ability to maintain optimal interferon-based therapy (see sections4.4 and5.1). Do not give this medication to anyone else, even if they have the same symptoms as you do. This medicine contains less than 1 mmol (23 mg)sodiumper tablet, ie essentially sodium-free. Note:- Make sure to contact your medical professional if adverse effects occur and become unmanageable. Paediatric patients 2 to 5 years of age: 2.5 mg/kg once a day for 6 months. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. There are certain medicines, including some prescription, non-prescription medicines, and vitamins, that interact with REVOLADE. You should not take these at the same time as REVOLADE or they may require dose adjustment while taking REVOLADE. These medications include some products within the following groups: Unlike TPO, eltrombopag treatment of normal human platelets does not enhance adenosine diphosphate (ADP) induced aggregation or induce P-selectin expression. If you become pregnant while taking this medication, contact your doctor immediately. Thanks everyone for your informative and kind replies. Patients of East/South-East Asian origin should receive a reduced dose of 1.25 mg/kg once a day for 6 months. Eltrombopag is also used to increase platelet counts for people with chronic hepatitis C virus infection, so that they can use interferon to treat the infection. This occurred in around 40% of those taking Revolade (25 out of 63) compared with around 3% (1 out of 29) of those who took placebo. Liver function:Liver disease or reduced liver function may cause this medication to build up in the body, causing side effects. STOP taking In this study, 40% of patients (17 out of 43) responded to treatment after 12 weeks, and in 65% of them (11 out of 17) the platelet count either increased by at least 20,000 per microliter or was stable without a need for blood transfusions. Those updates may contain important information about the medicine and its use of which you should be aware. If you are of East / Southeast Asian descent, you may need to start with alowerdoseof 25 mg. Children(1-5 years) the usual starting dose for ITP isone 25mg tabletof Revolade a day. What form(s) does this medication come in? Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Plasma eltrombopag Cmax and AUC(0-T) estimates for patients with HCV enrolled in phase III studies TPL103922 (ENABLE 1) and TPL108390 (ENABLE 2) are presented for each dose studied in Table 20. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. Buy Revolade 25 Tablet Online. Hepatitis C virus (HCV) Many patients with HCV have low platelet counts (thrombocytopenia), not only as a result of the disease but also due to some of the medicines that are used to treat the disease. Nonmedicinal ingredients:magnesium stearate, mannitol, microcrystalline cellulose, povidone, sodium starch glycolate, hypromellose, macrogol, titanium dioxide, iron oxide yellow, and iron oxide red. primary immune thrombocytopenia (ITP), a disease in which the patients immune system destroys platelets (components in the blood that help it to clot). Important serious side effects are liver problems and thromboembolic complications. Revolte 12.5 mg film-coated tablets are round, biconvex, white, and punched with GS MZ1 and 12.5 on one side. If you are pregnant, think you may be pregnant or are planning to have a baby speak to your doctor. You should not take more REVOLADE. www.medbroadcast.com/drug/getdrug/Revolade, are allergic to eltrombopag or any ingredients of the medication, flu-like symptoms (fever, cough, sore throat, sudden lack of energy), dizziness, lightheadedness, or fainting when rising from a sitting or lying position, signs of anemia (low red blood cells; e.g., dizziness, pale skin, unusual tiredness or weakness, shortness of breath), signs of a blood clot in the arm or leg (tenderness, pain, swelling, warmth, or redness in the arm or leg) or lungs (sharp chest pain that is worse when breathing in, difficulty breathing, coughing, coughing up blood, sweating, or passing out), signs of a blood clot in the spleen (severe pain in the upper left side of the abdomen, which may radiate to the left shoulder), signs of clotting problems (e.g., unusual nosebleeds, bruising, blood in urine, coughing blood, bleeding gums, cuts that don't stop bleeding) after stopping the medication, signs of depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide), signs of too much iron in the blood (e.g., fatigue, weakness, irregular heartbeat, joint pain, stomach pain), signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools), symptoms of an eating disorder (bulimia nervosa) (e.g., preoccupation with weight, repeated episodes of binging and forced vomiting), symptoms of a lung infection (e.g., cough, mucus, fatigue, shortness of breath, fever, chills), symptoms of a urinary tract infection (e.g., pain when urinating, urinating more often than usual, low back or flank pain), symptoms of low blood sugar (e.g., cold sweat, cool pale skin, headache, fast heartbeat, weakness), unusual infections (symptoms may include fever or chills, severe diarrhea, shortness of breath, prolonged dizziness, headache, stiff neck, weight loss, or listlessness), vision changes or blurred vision, halos, or eye floaters, blood infection (e.g., rapid heartbeat, fever, shaking, chills, nausea, vomiting, rapid breathing, decreased urination), signs of bleeding in the stomach (e.g., bloody, black, or tarry stools; spitting up of blood; vomiting blood or material that looks like coffee grounds) after stopping this medication, signs of a heart attack (e.g., chest pain or pressure, pain extending through shoulder and arm, nausea and vomiting, sweating), signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat), signs of stroke (e.g., sudden or severe headache; sudden loss of coordination; vision changes; sudden slurring of speech; or unexplained weakness, numbness, or pain in the arm or leg), symptoms of meningitis (e.g., fever, headache, stiff neck, light sensitivity, nausea, vomiting), antacids (e.g., aluminum hydroxide, magnesium hydroxide), calcium supplements (e.g., calcium carbonate, calcium citrate), hepatitis C antivirals (e.g., elbasvir, glecaprevir and pibrentasvir, grazoprevir, voxilaprevir), iron (e.g., ferrous fumarate, ferrous gluconate, ferrous sulfate), magnesium (e.g., magnesium hydroxide, magnesium oxide), "statin" anticholesterol medications (e.g., atorvastatin, lovastatin, simvastatin). REVOLADE may be taken with food low in calcium such as: Please discuss this matter with your doctor, pharmacist or healthcare provider. The complete address is provided on the website. Do not use this antiviral drug without consulting your medical professional, and make sure to share and discuss any concerns you might have before beginning therapy with Revolade (Eltrombopag) tablets. You must use a reliable method of contraception (a way to prevent you from becoming pregnant) during treatment with REVOLADE and for at least 7 days after you stop taking REVOLADE.
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